Research topics Development of automated synthesis procedures for radiopharmaceuticals with high molar activity (Am) and quality according to GMP regulations Optimising 18F-radiofluorination methods (electrophilic, transition metal mediated and nucleophilic) for simplicity and high Am (Fig. 1) Optimising target performance, 11C-labelling agent pathways and synthesis methods for simplicity, high yields and Am (Fig. 2) [11C]Phosgene Figure 1. Production paths of 18F-labelled radiopharmaceuticals at Turku PET Centre Figure 2. Production paths of 11C-labelled radiopharmaceuticals at Turku PET Centre
