Research topics

× Development of automated synthesis procedures for radiopharmaceuticals with high molar activity (Am) and quality according to GMP regulations

  • Small molecules
  • Peptides
  • Affibodies (Fab)

× Optimising 18F-radiofluorination methods (electrophilic, transition metal mediated and nucleophilic) for simplicity and high  Am (Fig. 1)

Figure 1. Production paths of 18F-labelled radiopharmaceuticals at Turku PET Centre

× Optimising target performance, 11C-labelling agent pathways and synthesis methods for simplicity, high yields and Am (Fig. 2)

Figure 2. Production paths of 11C-labelled radiopharmaceuticals at Turku PET Centre

× Radiometal labelling of novel chelating agents, their in vivo characterisation and utilisation in the labelling of bioactive macromolecules for PET imaging